منابع مشابه
Collagen and elastin fibres.
PROCOLLAGEN-COLLAGEN CONVERSION The first extracellular step after secretion is the proteolytic cleavage of these Nand C-terminal nonhelical regions of procollagen (Bornstein, 1974). The actual location of cleavage of these extension peptides is not known, but they are probably removed during the formation of the fibre and may take part in fibrogenesis. The intermediates in the conversion of pr...
متن کاملMicrocrimped collagen fiber-elastin composites.
Adv. Mater. 2010, 22, 2041–2044 2010 WILEY-VCH Verlag G T IO N Emerging biomaterials based upon analogues of native extracellular matrix proteins provide an opportunity to create protein scaffolds that mimic tissue mechanical behavior and guide cellular responses. However, in order to reproduce macroscale tissue properties, protein analogues must be endowed with appropriate microstructural feat...
متن کاملMatrix metalloproteinase interactions with collagen and elastin
Most abundant in the extracellular matrix are collagens, joined by elastin that confers elastic recoil to the lung, aorta, and skin. These fibrils are highly resistant to proteolysis but can succumb to a minority of the matrix metalloproteinases (MMPs). Considerable inroads to understanding how such MMPs move to the susceptible sites in collagen and then unwind the triple helix of collagen mono...
متن کاملQuantitative phase measurements of tendon collagen fibres.
Collagen is the main component of structural mammalian tissues. In tendons, collagen is arranged into fibrils with diameters ranging from 30 nm to 500 nm. These fibrils are further assembled into fibres several micrometers in diameter. Upon excessive thermal or mechanical stress, damage may occur in tendons at all levels of the structural hierarchy. At the fibril level, reported damage includes...
متن کاملAlmutairi, Cootes, Kadler: Tracking Collagen Fibres
Serial block-face scanning electron microscopy (SBF-SEM) has become an important modality for examining small structures in biology, and new instruments are capable of gathering large volumes of data. Analysing these datasets manually is difficult because of the number of individual images involved. Objects of interest often span many slices, and must be tracked by the user through these slices...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1978
ISSN: 0021-9746
DOI: 10.1136/jcp.s3-12.1.49